A bit of art history,
I discoverd a interesting painter Patrick Nasmyth
He managed to paint using his left hand after he had injury to his right hand and he was deaf due to a illness. His financial affairs were chaotic and consequently he never managed to make any real money from his paintings, he paid great attention to brickwork and fore ground in his paintingDetail Here
More info here
I found it interesting that even though he was deaf he seemed to be able to get round this problem also the problem with his hand must have caused numerouse problems for him,.
it was during a sketching exhibion in august 1631 that he was caught out in a thunderstorm and caught a cold which turned to influenca and he subsequently died.